منابع مشابه
Studies on the Eczematous Sensitization Iv. Sensitization to Metadinitrobenzene and Its Relation to 2:4 Dinitrochlorobenzene*
In the study of sensitizations to simple chemicals, there are two somewhat related chemical problems. One is the nature of the union between the sensitizing chemical and the tissues of the host in order to engender the eczematous sensitization, and the other is in what chemical respects can a substance that is capable of evoking a reaction in the already sensitized animal deviate from the paren...
متن کاملStudies in Rh Sensitization
By ALEXANDER S. WIENER, M.D., F.A.C.P., RAFFAELE NAPPI, M.D. AND EVE B. GORDON I N THE PRECEDING PAPER’ our methods for performing Rh antibody titrations were described in detail, with special reference to the precautions taken to insure objective and reproducible results. Using these technics, it was shown that pregnancies with Rh-negative fetuses and the birth of Rh-negative babies have no si...
متن کاملStudies on Early Allergic Sensitization in the Lithuanian Birth Cohort
Cohort studies are of great importance in defining the mechanism responsible for the development of allergy-associated diseases, such as atopic dermatitis, allergic asthma, and allergic rhinoconjunctivitis. Although these disorders share genetic and environmental risk factors, it is still under debate whether they are linked or develop sequentially along an atopic pathway. The current study was...
متن کاملStudies on the Sensitization of Animals with Simple Chemical Compounds
The fate of (14)C-labeled allergens injected intradermally into guinea pigs, namely picryl chloride (PCl*) and 2:4 dinitrochlorobenzene (DNCB*), was followed during the induction period of delayed hypersensitivity. Both chemicals were applied in a single injection into one ear in amounts that approached their minimal sensitizing doses (PCl, 0.25 microg; DNCB, 5.0 microg). Radioactivity in the v...
متن کاملStudies in Sensitization to Skin
1. Techniques for the preparation of skin antigen suitable for intramuscular injection in rabbits, and of skin antigens (autolysate) for serological experiments are described. 2. A method was evolved which produced a soluble skin antigen (autolysate) suitable for performing precipitin tests. 3. Injection of the rabbit skin antigen and of staphylococcus toxin in rabbits resulted in the formation...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1955
ISSN: 0022-202X
DOI: 10.1038/jid.1955.46